Gastrointestinal stromal tumours (GIST)
نویسندگان
چکیده
منابع مشابه
Review article: the biology, diagnosis and management of gastrointestinal stromal tumours.
BACKGROUND Gastrointestinal stromal tumours (GIST) are the most common mesenchymal tumours of the gastrointestinal tract with an increasing incidence. AIMS To review the biology, diagnosis and treatment of gastrointestinal stromal tumours. METHODS A PubMed search using the phrases 'Gastrointestinal stromal tumor', 'imatinib', 'c-kit'. RESULTS The diagnosis of GIST is established by histol...
متن کاملGastrointestinal stromal tumours at the University of Nigeria Teaching Hospital Enugu, Nigeria: an immunohistochemical study of GIT mesenchymal tumours.
Mesenchymal tumours of the gastrointestinal tract (GIT) are uncommon. Recent progress in the understanding of the biology and origin of these tumours has led to their reclassification. A new subclass designated Gastrointestinal Stromal Tumours (GIST) is diagnosed based on the presence of a mutational over expression of c-kit protein that is thought to be critical in the pathogenesis of these tu...
متن کاملBleeding Jejunal GIST: An uncommon cause of Gastrointestinal Bleeding.
Gastrointestinal stromal tumours (GIST) are rare gastrointestinal tumours and are one of the causes of obscure gastrointestinal bleeding. We report a case of massive gastrointestinal bleeding secondary to bleeding jejunal GIST in a 43 years old gentleman. Endoscopic intervention failed to identify the source of bleeding and CT Angiography (CTA) showed a jejunal mass and patient underwent laparo...
متن کاملGastrointestinal Stromal Tumor in the Stomach Co-Existent with Renal Cell Carcinoma
Gastrointestinal stromal tumours (GIST) are the most common mesenchymal tumours of the gastrointestinal system (GIS). They may co-exist with renal cell cancers (RCC). While a couple of cases have been reported in literature, these are in the form of case reports. This case report presents the case of a patient with GIST in the stomach and simultaneously detected RCC. Within the scope of the tre...
متن کاملGastrointestinal Stromal Tumuor- Case Report and a Review of the Literature
Gastrointestinal stromal tumours (GIST) are rare mesenchymal tumours, comprising 1% of all GI malignancies. This is a report of a middle-aged man diagnosed with GIST of the duodenum. He had gastrojejunostomy and para-aortic lymph node biopsy for histology. He was subsequently commenced on 5-fluorouracil but with little response.
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